2022 AMI Online Salon

Pathophysiology of acute appendicitis

Project Details

  • Entrant Name:  Andrew Rekito
  • Client: Journal of the American Medical Association
  • Copyright: American Medical Association, 2021
  • Medium/software used: Photoshop/Illustrator
  • Final presentation format: Print and web publication
  • Primary Audience: Primary care physicians

Project Description

Acute appendicitis is the most common abdominal emergency in the world. This figure provides initial background pathophysiology information for an article covering the most current data on clinical diagnosis and treatment of the condition. It describes the initial cause of appendiceal outlet obstruction, progression of the subsequent inflammatory response with effects on the wall of the appendix, and eventual necrosis and rupture into the abdominal cavity. The figure was designed for color print and web publication, but measures were taken to account for visually impaired readers. Anatomical structures and pathology effects were rendered with value and texture variations in mind then evaluated in grayscale and two colorblindness preview modes in Illustrator to ensure hue shift was not the only identifier for progressive changes in the images. Heading text and labels are solid black and a few select dark colors with appropriate underlying effects to ensure legibility. Some labels could not be placed over lighter surfaces and could be more difficult to read, so high-contrast text boxes with key descriptions were added to create clear correlation of the images to the overall message of the figure.