2022 AMI Online Salon

Neurofibromatosis Type II

Project Details

  • Entrant Name:  Allison Pardieck
  • Client: University of Illinois at Chicago
  • Copyright: Allison Pardieck, 2022
  • Medium/software used: Blender 3D, Pixologic ZBrush, Adobe Photoshop
  • Final presentation format: Educational poster
  • Primary Audience: Physicians

Project Description

Neurofibromatosis (NF) is a complex genetic, autosomal dominant disorder that can directly affect the central nervous system. Patients with NF experience tumor growth on nervous tissue, and the presentations of NF are divided into three types based on where the tumors originate. NF Type II is caused by acoustic neurofibromas that press on the cranial nerve VIII. Damage to this nerve negatively impacts the cochlea and semicircular canals, resulting in hearing loss and balance issues. NF is a source of disability for pediatric and adult patients around the world. While tumors are commonly associated with cancer in the minds of physicians and patients, it is important to consider that benign tumors are also responsible for debilitating damage to the human body. Because NF is autosomal dominant, it persists regardless of its rarity. Physicians should be aware of this presentation of NF when addressing hearing and balance problems in their patients, especially in lower-income areas where access genetic testing is hard to procure. NF does not improve on its own, and receiving accurate treatment relies on the physicians’ ability to recognize the symptoms and presentation.