2022 AMI Online Salon

Human BioMolecular Atlas Program (HuBMAP) Exploration User Interface

Project Detail

  • Entrant Name:  Heidi Schlehlein
  • Client: Indiana University
  • Copyright: NIH Human BioMolecular Atlas Program (HuBMAP), 2022
  • Medium/software used: ZBrush, Maya, Angular, deck.gl, 3D Slicer
  • Final presentation format: Web-based platform
  • Primary Audience: Biomed researchers and practitioners, general public

Project Description

The Human Biomolecular Atlas Program (HuBMAP) will develop the next generation of molecular analysis technologies and computational tools, and generate foundational tissue maps in order to accelerate the construction of an atlas of the human body at single-cell resolution for understanding the relationship between tissue organization and function. HuBMAP has created an authoritative ontology of anatomical structures, cell types, and biomarkers; this metadata is then linked to three-dimensional reference objects in the size and shape of human organs, functional tissue units, and anatomical micro-structures. Registered tissue data, collected from tissue mapping centers across the world, are registered online into the Registration User Interface. This data can be explored across multiple scales and in the context of an atlas via the Exploration User Interface (EUI). The EUI supports navigation by multiple coordinate systems, including spatial, physiologic, and organ-based browsing. By creating an atlas based on tissue samples from across the entire human population, researchers and the general public will be able to access extremely detailed information from diverse human populations.