2022 AMI Online Salon

Fibrodysplasia Ossificans Progressiva Educational Kit

Project Details

  • Entrant Name:  Jackie Meyer
  • Client: Ipsen
  • Copyright: One World DMG, 2021
  • Medium/software used: Various 3D and 2D programs
  • Final presentation format: 3D model and illustrated booklet
  • Primary Audience: Healthcare Providers

Project Description

Fibrodysplasia ossificans progressiva (FOP) is an extremely rare and debilitating genetic disease. It can be difficult for physicians to recognize early signs and symptoms, despite a few easily identifiable features. FOP is characterized by a pattern of soft tissue inflammation followed by formation of heterotopic bone. Before ossification occurs, flareups may be mistaken for other conditions (eg, tumors), which can lead to unnecessary testing. Biopsies, as well as intramuscular injections and surgery, can provoke additional flareups/ossification and must be avoided. Early diagnosis is paramount to limiting iatrogenic harm. This model was created to educate healthcare providers (HCPs) so that they may be able to identify FOP patients sooner. The spine, ribcage and intercostal muscles were chosen because the upper back is a common site of soft tissue swellings and later in life, many patients suffer from complications of thoracic insufficiency syndrome as a result of heterotopic bone buildup. Subcutaneous tissue is included for the flareup stage, enabling HCPs to palpate the skin and feel a representation of inflammatory swellings. When the top half is removed, muscle degradation with angiogenesis can be seen. The accompanying booklet provides important information about the pathophysiology, disease progression and key clinical considerations. Pharmaceutical reps are traveling around with these kits and bringing them into offices to educate HCPs and promote awareness of FOP.