2022 AMI Online Salon

Corneal Wound Healing and the Role of Inflammation

Project Detail

  • Entrant Name:  Sarah Hennessey
  • Client: Augusta University
  • Copyright:  Sarah Sutton and Augusta University, 2022
  • Medium/software used: Maxon Cinema 4D, Redshift, Adobe AfterEffects
  • Final presentation format: .mp4
  • Primary Audience: Researchers and Ophthalmologists

Project Description

Corneal blindness is the 4th leading cause of blindness, affecting the productivity and quality of life of nearly 5 million people worldwide. Typically, the cornea can heal quickly on its own; however, in some individuals, such as those with diabetes, the healing process may be delayed, resulting in significant morbidity. Better understanding the mechanism of corneal wound healing will enable researchers to identify and develop treatments that accelerate the process, which will be quite beneficial to patients with these painful wounds.This animation demonstrates the latest innovative research on the process of corneal wound healing, with emphasis on the role of inflammation, and introduces the novel concept that a naturally occurring lipid, dioleoyl-phosphatidylglycerol, may enhance the healing process.The animation accompanies a comprehensive review of the corneal healing process, which highlights a deficit in ocular care that would benefit from further research. The overarching goal is to eventually lead to an improvement in corneal health for millions of people worldwide.