2021 AMI Online Salon

Omega Therapeutics Epigenomic Programming MOA

Project Detail

  • Entrant Name:  David Ehlert
  • Other Contributors:  Inessa Stanishevskaya, Brandon Keehner
  • Client: Omega Therapeutics
  • Copyright: Omega Therapeutics, 2021
  • Medium/software used: C4D, After Effects, Adobe Illustrator
  • Final presentation format: Website video
  • Primary Audience: Investors, scientific community (KOLs), potential talent and partners

Project Description

The challenge involved creating an animation that not only introduced Omega’s groundbreaking platform of epigenomic programming in a high-level scientific manner but also a relatively unfamiliar biological structure, known as the insulated genomic domain (IGD). One goal was to create awareness and understanding of what IGDs are, where they’re located (through a visual change in magnitudes of scale from cell-nucleus-chromosome/chromatin-IGD), and how different types of disruptions in them can contribute to gene under/overexpression and thus disease. The other goal was to introduce Omega’s ability to computationally map and identify specific IGD targets and to create Omega Epigenomic Controllers- their structure, function, and ultimate use for restoring IGD structures from diseased states.