2021 AMI Online Salon

Heart attack tissue made less hostile to curative stem cells with sEH inhibitor

Project Details

  • Entrant Name:  Zina Deretsky
  • Client: UC Davis Health
  • Copyright: Level Five Graphics, Inc., 2020
  • Medium/software used: Adobe Illustrator, Adobe Photoshop
  • Final presentation format: Information graphic on the web for the lab that is pioneering the treatment
  • Primary Audience: Interested lay audience

Project Description

Previously helping the tissue in the heart damaged by heart attack with stem cells was a lofty goal but unachievable. The damaged tissue  was such a hostile environment, the stem cells could not take. However, Dr. Nipavan Chiamvimonvat and Dr. Padmini Sirish of UC Davis discovered that using sEH inhibitor to treat the tissue first (something that could be applied orally in pill form), helped subdue the hostility in the tissue to such a degree that stem cells were able to become seeded and not perish. A huge advancement in heart attack medicine!