2020 Online Salon
Ketamine Disrupts Visuospatial Working Memory in Prefrontal Cortex
- Entrant Name: Kelly Bullock
- Membership Type: Professional Submission
- Address: Mitchell, Ontario Canada
- Client: Dr. Julio Martinez-Trujillo
- Copyright: 2020 Kelly Bullock
- Medium/software used: Adobe Illustrator
- Final presentation format: Journal Cover
- Primary Audience: Scientists
Working memory is the ability of primates to manipulate and hold mental representations used to guide behavior. The clients’ research article demonstrates the role of the lateral prefrontal cortex in mediating working memory during naturalistic navigation.
This cover image was designed to showcase the article’s main story by intimating the mechanism of action of ketamine in the prefrontal cortex. In the image, the ketamine ‘turns off’ the working memory activity like a light.
The library, a visual analogy of working memory, shows books flying off the shelves and re-organizing dynamically. Where the ketamine attaches to an NMDA receptor, the activity is stymied. This article and cover submission are currently out for review.