2019 AMI Online Salon

Treating Depression with Escitalopram

Project Details

  • Company/Institution: University of Toronto

  • Entrant Name: Contessa Giontsis

  • Membership Type: Student Submission

  • Other Contributors:                         

  • Address: Scarborough,Canada

  • Client: Faculty Advisor: Derek Ng

  • Medium/software used: Cinema4D, Chimera, Photoshop and Illustrator

  • Final presentation format:Print, 2 page spread in a magazine

  • Primary Audience: Lay audience

Project Description

Depression is the leading cause of disability worldwide. Drugs that treat depression are commonly explained through text-heavy research papers that are difficult for a lay audience to understand. I created this two-page spread for a popular science magazine (e.g., Scientific American) to illustrate how escitalopram interacts with the serotonin transporter protein to treat depression. This illustration compares, at the molecular level, the interactions between serotonin, the serotonin transporter protein, the primary and allosteric binding sites, and the serotonin receptor during a depressive state vs. treated state.