2019 AMI Online Salon

Transcription in Myc-Related Cancers

Project Details

  • Entrant Name: Dani Bergey

  • Membership Type: Student Submission

  • Other Contributors:                         

  • Address: Chicago,IL

  • Client: Ali Shilatifard, PhD (Simpson Querrey Center for Epigenetics); Christine Young, Kevin Brennan, and Deb Milkowski (UIC BVIS)

  • Medium/software used: Visual Molecular Dynamics, Pixologic ZBrush, Autodesk 3ds Max, Adobe After Effects

  • Final presentation format: Animation (mp4, 1280x720px)

  • Primary Audience: Broad, college biology students to individuals with an advanced biology degree

Project Description

This animation was created to explain a research endeavor at Northwestern University’s new epigenetics center. The public has a significant lack of understanding of genetics, and this animation aimed to be a step towards correcting that. The purpose and challenge was to create an engaging, educational, and scientifically-accurate story for a broad audience. I used visual design methods to establish distinct learning goals for three audience subgroups that were distinguished by their biomedical background. Learning goals were organized into modules of verbal and visual information that directly informed the script and storyboard. An extensive literature review was conducted for ~20 molecular structures in this animation–many of which have large disordered regions. By studying common practices and reflecting on the purpose, I made informed artistic decisions about representation, such as using surface representations rather than ribbon to emphasize intermolecular interactions.