2019 AMI Online Salon

Immunization with a Nanoparticle Vaccine Containing an Epstein-Barr Virus (EBV) Glycoprotein Complex

Project Details

  • Company/Institution: National Institutes of Health
  • Entrant Name: Ryan Kissinger
  • Membership Type: Professional Submission
  • Address: Hamilton, MT
  • Client: Dr Jeffrey Cohen
  • Medium/software used: Cinema 4D Octane Render
  • Final presentation format: Cover
  • Primary Audience: Researchers

Project Description

In creating this image for a recently published edition of Immunity, I was tasked with producing a visual that could captivate the viewer immediately and yet maintain the central message of the researcher’s findings. This image illustrates how Epstein-Barr virus nanoparticles composed of a ferritin core (yellow) and covered in antigenic epitopes on glycoproteins (dark blue), cross-link with B cell receptors (blue antibody molecules) on B cells (brown) to induce potent neutralizing antibodies. The antibodies target a site on the EBV glycoprotein complex critical for fusion and inhibit glycoprotein-mediated cell membrane fusion.