2019 AMI Online Salon

The Pupillary Light Reflex Constriction Pathways

Project Details

  • Entrant Name: John Karapelou
  • Membership Type: Professional Submission    
  • Address: South Euclid, OH
  • Client: AlgometRx
  • Medium/software used: Digital: Lightwave, Keyshot, Photoshop
  • Final presentation format: PowerPoint, web
  • Primary Audience: physicians and corporate investors

Project Description

To depict the basic pathways of the pupillary light reflex and showing activated nerves causing constriction of the pupil. Shown are sensory afferent nerve fibers being conducted through the optic nerve from the eye to the midbrain, where they synapse with interneurons in the pretectal area (nucleus) which send fibers to the ipsilateral and contralateral accessory motor nucleus. There they synapse with preganglionic pupilloconstriction neurons whose efferent fibers exit via the oculomotor nerve to the ciliary ganglion where they synapse with postganglionic neurons that project efferent fibers out via the short ciliary nerves to the eyeball, terminating at the iris sphincter m. The terminal is shown with an active signal to the iris, which has now constricted. Part of a multi-part illustration series depicting the reflex and drugs that affect it.