2019 AMI Online Salon

Collective Epithelial Metastasis

Project Details

  • Company/Institution: The Children’s Hospital of Philadelphia

  • Entrant Name: Brittany Bennett

  • Membership Type: Student Submission

  • Other Contributors:                         

  • Address: Royal Palm Beach, FL

  • Client: Andrew Ewald, PhD

  • Medium/software used: Imaris, Cinema 4D, Adobe Photoshop, Adobe Illustrator

  • Final presentation format: Powerpoint Slide

  • Primary Audience: Non-specialist scientists, patient advocates, investors

Project Description

The client’s lab focuses their research on this cellular moment that is key to the metastasis of epithelial tumors: the moment when cancer cells spread away from the original tumor. The Lab captures many compelling microscopy time-lapse videos of this event, but these fluorescent images on a black background do not intuitively communicate to audiences outside of cell-biology. This illustration was created to show the cell types of interest in the peak moment of action in a visual language that is more clear to the intended audience. The 3D image was created using real time-lapse 3D microscopy data from the lab, resulting in a scene that is accurate to the cellular dynamics observed in the Lab. The purpose was to create a visual schema that made it easier for the audience to understand the Lab’s raw microscopy data included in the presentation.