David Goodsell 

Experimental information from microscopy, structural biology, and bioinformatics may be combined to create structural models of entire cells with molecular detail. I will describe the tools that we are building to create and visualize these models, and applications of these tools to research and science outreach.

Speaker Bio

David Goodsell currently holds a dual appointment as Associate Professor of Molecular Biology at the Scripps Research Institute and Research Professor at Rutgers State University. I divide my time between research and science outreach. My research centers on methods for computational structural biology and their application to drug design, protein function prediction, and modeling of the molecular structure of entire cells. Current work includes development of AutoDock, the most widely-used computational docking program in the scientific community, and CellPack, a new method for creating three-dimensional atomic models of large portions of cells. I am currently applying these methods to HIV drug resistance and structure and function of bacterial cells. In my science outreach work, I have developed new visual methods for exploring molecular and cellular structure. This includes two decades of work on depiction of the cellular mesoscale, and development of non-photorealistic rendering methods for molecular and cellular subjects. I currently create outreach materials for the RCSB Protein Data Bank, including a popular monthly column that presents molecular structure and function for general audiences. I have written four general-interest books on molecular biology, cell biology and bionanotechnology, and have collaborated with science museums, filmmakers, educators and popular authors on the creation of educational and outreach materials.