2018 AMI Online Salon

Tick-Borne Encephalitis Virus Neutralization

Project Details

  • Artist(s):  Vondel Mahon; Baltimore, Maryland
  • Client: Fabian De Kok-Mercado, Sandra Gabelli
  • Copyright: © 2018 Vondel Mahon
  • Medium / software used: Adobe Photoshop, Adobe Illustrator, Cinema 4D, PyMOL, ePMV
  • Final presentation format: Journal Cover
  • Primary audience: Research Scientist

Project Description

The tick-borne encephalitis virus infects neuronal cells, causing meningitis and encephalitis. New research indicates that antibody 19/1786 neutralizes the virus by preventing it from fusing with the membrane of the host cell. The background scene shows the virus successfully binding to the host cell while the foreground illustrates a vital stage during which the antibodies coat the virus and block it from fusing with the host cell. This demonstrates the antibody’s role in potential treatments and vaccine design. The goal of the assignment was to create an editorial cover illustration by utilizing molecular structures from the Protein Data Bank to build a 3D scene with an engaging sense of atmosphere.