2018 AMI Online Salon

T Cells Triggered to Fight Cancer

Project Details

  • Artist(s):  Allison Bruce
  • Contributors: Teemu Junttila, Alex Ritter,  ; Brisbane, California
  • Client: Genentech, Inc.
  • Copyright: © 2017 Genentech, Inc.
  • Medium / software used: Alcohol ink, Adobe Photoshop
  • Final presentation format: Print Journal Cover
  • Primary audience: Scientific Community

Project Description

This illustration highlights the function of a newly developed antibody, anti-FcRH5/CD3, for multiple myeloma immunotherapy. The T-cell-dependent bi-specific (TDB) antibody is designed to trigger T cells to kill myeloma tumor cells by releasing lytic granules (shown in pink) and causing apoptosis of the cancer cell (shown in orange). The painting is based on original super-resolution images captured by Alex Ritter using structured illumination microscopy.