2018 AMI Online Salon

Central Dogma and Genetic Medicine

Project Detail

  • Artist(s):  Fabian de Kok-Mercado
  • Contributors: Fabian de Kok-Mercado, Aileen O’Hearn; Chevy Chase, Maryland
  • Client: HHMI
  • Copyright: © 2018 HHMI
  • Medium / software used: Maxon Cinema 4D, Photoshop, HTML5
  • Final presentation format: Web based interactive (desktop and mobile)
  • Primary audience: High school and undergraduate science educators and students

Project Description

This interactive uses the central dogma as a model for exploring how modern molecular biology technologies can be used to treat genetic diseases by showcasing different steps in the pathway from genetic information to proteins. High school and undergraduate students and science educators can explore the self-paced interactive by scrolling down the page and engaging with visualized steps in the central dogma pathway. Illustrations in the pathway are based on published molecular data and are presented at relative scale. Each step is associated with a treatment strategy for a particular genetic disease that is being studied through experimental models or human clinical trials. Students can explore treatment strategies in a variety of formats by selecting the plus signs associated with each step. Educators can use this interactive in a variety of courses, ranging from first-year high school biology to undergraduate molecular biology electives and biotechnology-focused courses.